Back

Statistics for Bioinformatics and eScience (StatBI/E)

NMAK14029U - SCIENCE

Passed: 95%, Average grade: 7.98, Median grade: 7

Description

The course will take the participants through the following content:

 

  • Standard discrete and continuous distributions, descriptive methods, Bayes’ theorem, conditioning, independence, and selected probability results.
  • Simulation.
  • Mean, variance, estimators, two-sample comparisons.
  • Maximum likelihood and least squares estimation.
  • Standard errors and confidence intervals (e.g. via bootstrapping).
  • Correlation, (generalized) linear and non-linear regression.
  • The statistical programming language R and R notebooks.

Knowledge:



The basic concepts in mathematical statistics, such as:

  • Probability distributions
  • Standard errors and confidence intervals
  • Maximum likelihood and least squares estimation
  • Hypothesis testing and p-values
  • (Generalized) Linear and non-linear regression



Skills:

  • Master basic implementation in R and generation of analysis reports using R notebooks.
  • Use computer simulations for computations with probability distributions, including bootstrapping.
  • Compute uncertainty measures, such as standard errors and confidence intervals, for estimated parameters.
  • Compute predictions based on regression models taking into account the uncertainty of the predictions.
  • Assess a fitted distribution using descriptive methods.
  • Use general purpose methods, such as the method of least squares and maximum likelihood, to fit probability distributions to empirical data.
  • Summarize empirical data and compute relevant descriptive statistics for discrete and continuous probability distributions.



Competences:

  • Formulate scientific questions in statistical terms.
  • Interpret and report the conclusions of a practical data analysis.
  • Assess the fit of a regression model based on diagnostic quantities and plots.
  • Investigate scientific questions that are formulated in terms of comparisons of distributions or parameters by statistical methods.
  • Investigate scientific questions regarding association in terms of (generalized) linear and non-linear regression models.

Recommended qualifications

IMPORTANT: This course requires and assumes quantitative/​mathematical prior knowledge equivalent to a MatIntro or equivalent course!



MSc students and BSc students in their 3rd year with MatIntro or an equivalent course.



Academic qualifications equivalent to a BSc degree is recommended.

Coordinators

Sebastian Weichwald

sweichwald@math.ku.dk

Exam

Continuous Assessment

Course Info

Level: Master

ECTS: 7.5

Block(s): 2

Group(s): C

Go to official page

Department(s)

  • Mathematics

Workload

Lectures35h
Preparation118h
Practical Exercises21h
Exam32h

Total: 206h