Description

The course topics include: An introduction to analytical chemistry: choice of analytical methodology, sampling, sample preparation, chemical analysis, tools for quantitative chemical analysis, quality assurance. Extraction methods such as liquid-liquid extraction, solid phase extraction, super-critical fluid extraction and pressurised liquid extraction. Cleanup and fractionation methods. Introduction to Chromatography, high-pressure liquid chromatography (HPLC), gas chromatography (GC) and other chromatographic methods. Detector types with focus on mass spectrometry and hyphenated techniques such as GC-MS and LC-MS. Introduction to spectroscopic methods (UV-VIS, IR, X-ray, atomic absorption spectroscopy (AAS) and inductive coupled plasma mass spectrometry). Introduction to data processing, errors in chemical analyses, statistical analyses (including chemometrics) and data presentation. Method development, evaluation, validation and QA/QC measures.



Compulsory laboratory exercises comprise projects which involve sampling, extraction and cleanup, methods of analysis, data processing and data evaluation.

The course objective is to introduce the participants to modern instrumental techniques and analytical approaches within environmental- and soil chemistry, food chemistry and plant biology.



After completing the course the student should be able to:



Knowledge:

Describe the theory of sampling, sample preparation and sample preparation techniques

Refer to the chemical theory behind the use of modern instrumental techniques for quantitative chemical analysis

Describe how to identify unknown compounds by mass spectrometry and to measure their concentrations in environmental and food samples



Skills:

Develop and apply methods for separating chemical compounds in mixtures using chromatography

Perform quantitative chemical analysis of organic compounds and metals

Apply solid data processing and evaluation of analytical data



Competences:

Develop, validate and apply analytical methods in different field of research

Evaluate and discuss analytical chemical data from the literature.

Do problem solving in analytical chemistry

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